SOC Drugs

# 1. Target: VEGFA

Drugs

Model Evidence

21 regulons containing the target(s), VEGFA are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


Drugs in GBM Trials

# 1. Target: FNTA,FNTB

Drugs

Model Evidence

15 regulons containing the target(s), FNTA,FNTB are overactive in this patient.

Hallmarks Enrichment

HALLMARK_OXIDATIVE_PHOSPHORYLATION

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


2. Target: WEE1

Drugs

Model Evidence

11 regulons containing the target(s), WEE1 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


FDA Approved Drugs

# 1. Target: APP

Drugs

Model Evidence

41 regulons containing the target(s), APP are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


2. Target: PLA2G2A,PLA2G5

Drugs

Model Evidence

8 regulons containing the target(s), PLA2G2A,PLA2G5 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


3. Target: HBB

Drugs

Model Evidence

2 regulons containing the target(s), HBB are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


4. Target: VKORC1

Drugs

Model Evidence

2 regulons containing the target(s), VKORC1 are overactive in this patient.

Hallmarks Enrichment

HALLMARK_UNFOLDED_PROTEIN_RESPONSE

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


5. Target: CA2

Drugs

Model Evidence

15 regulons containing the target(s), CA2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


6. Target: ABL1

Drugs

Model Evidence

5 regulons containing the target(s), ABL1 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


7. Target: RTN4

Drugs

Model Evidence

3 regulons containing the target(s), RTN4 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


8. Target: FNTA,FNTB

Drugs

Model Evidence

15 regulons containing the target(s), FNTA,FNTB are overactive in this patient.

Hallmarks Enrichment

HALLMARK_OXIDATIVE_PHOSPHORYLATION

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


9. Target: FGF1

Drugs

Model Evidence

1 regulons containing the target(s), FGF1 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


10. Target: LOXL2

Drugs

Model Evidence

1 regulons containing the target(s), LOXL2 are overactive in this patient.

Hallmarks Enrichment

HALLMARK_UNFOLDED_PROTEIN_RESPONSE

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


11. Target: BSG

Drugs

Model Evidence

2 regulons containing the target(s), BSG are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


12. Target: NDUFA13

Drugs

Model Evidence

5 regulons containing the target(s), NDUFA13 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


13. Target: TSG101

Drugs

Model Evidence

2 regulons containing the target(s), TSG101 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


14. Target: PLA2G2A

Drugs

Model Evidence

2 regulons containing the target(s), PLA2G2A are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


15. Target: ELN

Drugs

Model Evidence

1 regulons containing the target(s), ELN are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


16. Target: TRPV4

Drugs

Model Evidence

1 regulons containing the target(s), TRPV4 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


17. Target: UGCG

Drugs

Model Evidence

50 regulons containing the target(s), UGCG are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


18. Target: MAPK1,MAPK3

Drugs

Model Evidence

19 regulons containing the target(s), MAPK1,MAPK3 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


19. Target: ABAT

Drugs

Model Evidence

16 regulons containing the target(s), ABAT are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


20. Target: TNFRSF1A

Drugs

Model Evidence

15 regulons containing the target(s), TNFRSF1A are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


21. Target: ATP1A1

Drugs

Model Evidence

69 regulons containing the target(s), ATP1A1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


22. Target: VEGFA

Drugs

Model Evidence

21 regulons containing the target(s), VEGFA are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


23. Target: OXTR

Drugs

Model Evidence

10 regulons containing the target(s), OXTR are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


24. Target: EEF2

Drugs

Model Evidence

10 regulons containing the target(s), EEF2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


25. Target: JAK2

Drugs

Model Evidence

18 regulons containing the target(s), JAK2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


26. Target: TNC

Drugs

Model Evidence

9 regulons containing the target(s), TNC are overactive in this patient.

Hallmarks Enrichment

HALLMARK_TNFA_SIGNALING_VIA_NFKB

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


27. Target: HSPA8

Drugs

Model Evidence

27 regulons containing the target(s), HSPA8 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


28. Target: ABCA1

Drugs

Model Evidence

16 regulons containing the target(s), ABCA1 are overactive in this patient.

Hallmarks Enrichment

HALLMARK_TNFA_SIGNALING_VIA_NFKB

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


29. Target: HRH1

Drugs

Model Evidence

42 regulons containing the target(s), HRH1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


30. Target: ANGPT2,VEGFA

Drugs

Model Evidence

31 regulons containing the target(s), ANGPT2,VEGFA are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


31. Target: HRH1,SLC6A2

Drugs

Model Evidence

42 regulons containing the target(s), HRH1,SLC6A2 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


32. Target: SOD1

Drugs

Model Evidence

5 regulons containing the target(s), SOD1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


33. Target: ACVR2B

Drugs

Model Evidence

5 regulons containing the target(s), ACVR2B are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


34. Target: IFNGR2

Drugs

Model Evidence

24 regulons containing the target(s), IFNGR2 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


35. Target: CA2,CA4

Drugs

Model Evidence

15 regulons containing the target(s), CA2,CA4 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


36. Target: SERPINE1

Drugs

Model Evidence

46 regulons containing the target(s), SERPINE1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


37. Target: ANGPT2

Drugs

Model Evidence

21 regulons containing the target(s), ANGPT2 are overactive in this patient.

Hallmarks Enrichment

HALLMARK_TNFA_SIGNALING_VIA_NFKB

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


38. Target: PGF,VEGFA

Drugs

Model Evidence

21 regulons containing the target(s), PGF,VEGFA are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

Network Plots

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